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Why was John Howard Northrop awarded Noble Prize in 1946?

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Why was John Howard Northrop awarded Noble Prize in1946?The 1946 Nobel Prize in Chemistry was received by John Howard Northrop, a biochemist from the United States, along with James Batcheller Sumner and Wendell Meredith Stanley. This group of scientists received the honor for their work isolating, crystallizing, and researching viruses, proteins, and enzymes.

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